Tutorial · 7 min
How to use Risk of Bias & GRADE
RoB 2, ROBINS-I, QUADAS-2 and evidence profiles
Run the standard bias instruments domain by domain and build a GRADE evidence profile or summary-of-findings table from your judgements.
Before you start
- • Full texts of the included studies
Steps
- 1
Open Risk of Bias & GRADE
Sidebar → Risk of Bias & GRADE.
- 2
Pick the right instrument
RoB 2 for randomised trials, ROBINS-I for non-randomised studies, QUADAS-2 for diagnostic accuracy.
- 3
Answer the signalling questions
Work domain by domain with the full text open; the tool derives the domain judgement from your answers.
- 4
Build the GRADE profile
Rate down for risk of bias, inconsistency, indirectness, imprecision and publication bias to produce a summary of findings table.
- 5
Export the assessment
Download the traffic-light table and the evidence profile as PDF or CSV.
Tips
- • Save a checklist preset so the same instrument and rationale wording is reused across studies.
Troubleshooting
Which tool for a cohort study?
ROBINS-I. RoB 2 only applies to randomised designs.